PHARMACEUTICAL CALCULATION Test Questions

Experiment 6: Specific Gravity of Liquids

Objectives:

A.      Define specific gravity

B.      State and explain the Archimedes’ principle

C.      Describe the different methods of determining the specific gravity of a liquid and state their application, advantages, and limitations

D.      Determine the specific gravity of liquids using the appropriate / applicable method

E.       Calculate specific gravity of liquids

Test Questions:

1.       Define specific gravity:

2.       Differentiate true from apparent specific gravity

3.       Compare and contrast specific gravity and density

4.       What are the different methods of determining the specific gravity of liquids

5.       State the principle of Archimedes

6.       What is the application of specific gravity in the field of Pharmacy?

  

Experiment 7: Specific Gravity of Solids

Objectives:

A.      Define specific gravity

B.      State and explain the Archimedes’ principle

C.      Device a method for determining the specific gravity of solid depending on its physical form, density, and solubility in water, and other liquids

D.      Determine the specific gravity of solids using the appropriate method

E.       Calculate specific gravity of solids

Test Questions:

1.       What are the factors that must be considered in selecting the method to be employed

2.       Given the following data, compute for the specific gravity of the sample in each category:

a.       Solids heavier than and insoluble in water (one piece)

Weight of sample in air                  12.9057 g

Weight of sample in water           11.7704 g

b.      Solids heavier than insoluble in water (several pieces)

Weight of sample                                                                0.3132 g

Weight of volumetric flask + water                          164.4288 g

Weight of volumetric flask + water + sample       164.6768 g

c.       Solid heavier than and soluble in water

Weight of sample in air                                  2.7181 g

Weight of sample in mineral oil                  1.5623 g

d.      Solid heavier than and insoluble in water

Weight of sample in air                                     1.1488 g

Weight of sample in water                           18.8270 g

Weight of sinker in water                             17.2368 g

Weight of sample and sinker in water     14.8218 g

Experiment 8: Concentration Expression

Objectives:

A.      Define concentration

B.      Prepare a concentrated solution

Test Questions:

1.       Define concentration:

2.       Define the following concentration expressions:

a.       Mole

b.      Millimole

c.       Molarity

d.      Molality

e.      Normality

f.        mEq

g.       Percent (%)

h.      mg %

i.         ppm

j.        Mole fraction

k.       Osmalarity

l.         Osmolality

Experiment 9: Dilution of Solutions and Liquid Formulation

Objectives:

A.      Define dilution

B.      Calculate the volume or any quantitative measure, needed or the resultant strength by allegation methods

C.      Employ the aliquot method of measurement when necessary

D.      Prepare stock solutions; solution of different concentrations from stock solution or by mixing solutions of different strengths; dilute solutions of concentrated inorganic acids

Test Questions:

1.       Define dilution:

2.       Differentiate dilution / concentration from reducing / enlarging formulae:

3.       When do you employ the aliquot method of measurement? Illustrate.

4.       What are stock solutions?

5.       When do you prepare stock solutions?

6.       What are the two methods of Alligation? Illustrate.

Experiment 10: Calculation of Medication Dosage for Children

Objectives:

A.      Define dose

B.      Know the different expression of a dose

C.      Identify the different factors used as the basis in the calculation of dosage medication

D.      Know the different rules/formulae in calculating dosage for children

Test Questions:

1.       Define dose:

2.       What are the different expressions of a dose?

3.       Enumerate the different factors used as the basis in the calculation of dosage medication:

4.       What is the official household measuring equipment for liquids accepted by USP? Give its equivalent in millilitres:

5.       Which method is used for precise calculation of pediatric doses used by most physicians today? Why?

Experiment 11: Prescription Pricing

Objectives:

A.      Define Pharmacoeconomics

B.      Identify factors that bring about the importance of Pharmacoeconomics

C.      Know the different methods of prescription pricing:

Test Questions:

1.       What is Pharmacoeconomics?

2.       Identify and enumerate the different factors that bring about the importance of Pharmacoeconomics:

3.       What are the different methods of Prescription pricing?